The Neurobiology of Depression and Physical Exercise

Authored by: Michael J. Chen

Routledge Handbook of Physical Activity and Mental Health

Print publication date:  April  2013
Online publication date:  August  2013

Print ISBN: 9780415782999
eBook ISBN: 9780203132678
Adobe ISBN: 9781136477805


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Chronic severe stress often culminates in major depression. Whereas stress/depression atrophies neurons and dendrites, enjoyable physical exercise restores them. Exercise, therefore, is conducive to neuronal survival and is considered antidepressant. Herein, I start with discussing neuro-transmitters and gradually progress to how depression and exercise are involved in systemic diseases, such as metabolic disorders.

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