Orthopoxvirus

Authored by: Vinayagamurthy Balamurugan , Gnanavel Venkatesan , Veerakyathappa Bhanuprakash

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch96

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Abstract

There have been some reports on the emergence of human infections by pox viruses since smallpox was eradicated globally in 1979 [1]. However, different pox viruses such as cowpox virus (CPXV), buffalopox virus (BPXV), and vaccinia virus (VACV) (genus Orthopoxvirus [OPV]) and orf virus, bovine papular stomatitis, and pseudocowpox (genus Parapoxvirus) can cause very similar lesions in cattle and animal handlers [2]. In general, OPVs carrying genes responsible for host immune evasion pose a threat to livestock and humans as potential biowarfare agents.

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