Capripoxviruses (Sheeppox, Goatpox and Lumpy Skin Disease Viruses)

Authored by: E.H. Venter

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:


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Capripoxviruses are classified within the family Poxviridae and are the etiological agents of sheeppox (SPP), goatpox (GTP), and lumpy skin disease (LSD) of cattle. The causative viruses, sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV), are responsible for a generalized pox disease characterized by pyrexia, generalized skin lesions, ulcer-ative lesions in the mucous membranes of the mouth and nasal cavities, and lymphadenopathy. 1-4 Due to their transbound-ary capacity, capripoxvirus infections could become emerging diseases; the Office Internationale des Epizooties (OIE), or the World Organization for Animal Health, have to be notified of outbreaks. In endemic areas, they are of great economic significance to farmers and have a major impact on international trade in livestock and livestock products. The morbidity and mortality of SSP and GTP are very high and can reach 100% in naïve animals. In contrast, LSD is an occasionally fatal disease with morbidity averaging 10% and mortality 1% in affected herds, although mortality rates over 75% have been recorded.5

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