Marburg Virus

Authored by: Junping Yu , Hongping Wei

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch58

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Abstract

Marburg virus (MARV) is the causal agent of MARV disease (MVD) (formerly known as Marburg hemorrhagic fever) in human and nonhuman primates, which was first identified in 1967 during epidemics in Marburg and Frankfurt in Germany and Belgrade in the former Yugoslavia from importation of infected monkeys from Uganda [1,2]. Similar to the Ebola virus (EBOV) disease, MVD is a severe and highly fatal disease. Both MARV and EBOV are among the most virulent pathogens known to infect humans. Both diseases are rare, but have a capacity to cause dramatic outbreaks with high fatality. Despite significant progress in drug development for MVD [3], there are no approved vaccines or postexposure treatment drugs available yet. The predominant treatment is general supportive therapy.

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