Reticuloendotheliosis Viruses

Authored by: Dongyou Liu

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch23

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Abstract

Reticuloendotheliosis is a neoplastic disease of poultry caused by a group of reticuloendotheliosis viruses (REVs) belonging to the genus Gammaretrovirus, family Retroviridae. Affecting a variety of avian species such as chicken, turkey, duck, goose, pheasant, and peafowl, reticuloendotheliosis is characterized by immunosuppression, runting-stunting syndrome, chronic lymphomas, and chronic neoplasm, which resemble both Marek′s disease and avian leukosis. Interestingly, the etiologic agent for Marek′s disease is Marek′s disease virus (MDV) of the genus Alphaherpesvirus, family Herpesviridae, and that for avian leukosis is avian leukosis virus (ALV) of the genus Alpharetrovirus, family Retroviridae. These avian oncogenic viruses have a huge economic impact on poultry industry worldwide, and their overlapping disease profiles make differential diagnosis on clinical ground difficult, if not impossible. As the topics on MDV and ALV are covered in Chapters 17 and 87, the main focus here is REV.

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