Betanodavirus

Authored by: Dongyou Liu

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch2

 Download Chapter

 

Abstract

Betanodavirus is the etiological agent of viral nervous necrosis (VNN), also known as vacuolating encephalopa-thy and retinopathy (VER) or encephalomyelitis, which is a devastating viral disease affecting marine and freshwater fish species worldwide. First observed in 1986 on an aqua-culture farm of Japanese parrotfish (Calotomus japonicus) in Nagasaki, Japan, VNN was linked to loss of balance, necrosis in the brain and retina, and death of fish fry (of 6-25 mm length) during the summer (June-July) [1]. Almost simultaneously, VNN was discovered in Australia, Norway, and France, involving barramundi (Asian sea bass, Lates calca-rifer), turbot (Scophthalmus maximus), European sea bass (Dicentrarchus labrax), red-spotted grouper (Epinephelus akaara), striped jack (Pseudocaranx dentex) [2-5], and other cultured warm-water and cold-water marine fish species (n = 30) throughout the world [1]. Given its capacity to induce high mortality (80%-100%) in juvenile fish, VNN exerts huge economic and ecological burdens on aquaculture industry and wild marine species [6]. In this chapter, we focus on beta-nodavirus in relation to its taxonomy, morphology, genome structure, epidemiology, clinical features, pathogenesis, diagnosis, and control, together with stepwise molecular protocols for its identification and diagnosis.

 Cite
Search for more...
Back to top

Use of cookies on this website

We are using cookies to provide statistics that help us give you the best experience of our site. You can find out more in our Privacy Policy. By continuing to use the site you are agreeing to our use of cookies.