Avian Leukosis Virus

Authored by: Yongxiu Yao , Venugopal Nair

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch17

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Abstract

The leukosis/sarcoma (L/S) group of diseases encompasses a variety of transmissible benign and malignant neoplasms of chickens caused by members of the family Retroviridae [1]. The term "leukosis" embraces several different leukemialike proliferative diseases of the cells of the hemopoietic system due to avian leukosis virus (ALV), with an undertone that a leukemic blood picture is not always present [2,3]. The components of the hemopoietic system that may undergo neoplastic change include the lymphopoietic (lymphocytic) system, the erythropoietic (red cell) system, and the myelo-poietic (myelocytic) system. Presenting signs of the leukosis are mostly nonspecific (loss of appetite, weakness, emaciation, diarrhea, pale wattles). Lymphoid leukosis (LL) has been the most common form of L/S group of diseases seen in field flocks, although more recently, myeloid leukosis has become increasingly prevalent.

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