Chronic Wasting Disease

Authored by: Akikazu Sakudo , Takashi Onodera

Molecular Detection of Animal Viral Pathogens

Print publication date:  August  2016
Online publication date:  May  2016

Print ISBN: 9781498700368
eBook ISBN: 9781498700375
Adobe ISBN:

10.1201/b19719-ch100

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Abstract

Chronic wasting disease (CWD) belongs to a group of fatal neurodegenerative diseases in cervids and is an example of a transmissible spongiform encephalopathy (TSE). An extraordinary feature of CWD is its relatively high incidence in wild animals, despite its capability to affect both captive and free-living cervids. CWD infection in the wild appears to be limited to mule deer (Odocoileus hemionus) [1], white-tailed deer (Odocoileus virginianus) [2], Rocky Mountain elk (Cervus elaphus nelson) [3], and Shiras moose (Alces alces shirasi) [4]. Within endemic areas, transmission occurs intraspecifi-cally (among deer of the same species) and interspecifically (among cervids of different species) through direct or indirect contact with infected cervids.

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