Performance Assessment of Small Animal Imaging Systems and Common Standards

Authored by: Nancy L. Ford

Handbook of Small Animal Imaging

Print publication date:  April  2016
Online publication date:  February  2016

Print ISBN: 9781466555686
eBook ISBN: 9781466555693
Adobe ISBN:

10.1201/b19052-31

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Abstract

All imaging equipment produces a pictorial representation of the object that was imaged. Obtaining quantitative information from these images provides the true power behind the technology, taking the important step from a pretty picture to measured data that can be compared across study groups, between research studies, and across imaging platforms. Ensuring that the data obtained are reliable and accurate requires good image quality. In this chapter, image quality is described by various objective metrics that can be measured in most imaging platforms. To obtain the best images possible will require tailoring the imaging protocol for different studies; however, practical limitations may reduce the flexibility of the optimization process, particularly for in vivo studies. To ensure reliable results from the imaging equipment over time, quality assurance programs and industry standards are needed to identify when individual systems go out of calibration or are functionally unstable. Regular assessment of system performance will enable long-term studies to be performed without concerns about the validity of any results obtained from the images.

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