Plaque Assay for Bacteriophage

Authored by: Emanuel Goldman

Practical Handbook of Microbiology

Print publication date:  June  2015
Online publication date:  June  2015

Print ISBN: 9781466587397
eBook ISBN: 9781466587403
Adobe ISBN:

10.1201/b17871-9

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Abstract

The plaque assay, an indispensable tool for the study of bacteriophage, was described in the earliest publications on the discovery of these viruses. Felix d’Hérelle, credited as a codiscoverer of phage (along with Frederick Twort), described, in effect, the first plaque assay in 1917 [1], when he wrote the following:

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