Antibiotic Susceptibility Testing

Authored by: Audrey Wanger

Practical Handbook of Microbiology

Print publication date:  June  2015
Online publication date:  June  2015

Print ISBN: 9781466587397
eBook ISBN: 9781466587403
Adobe ISBN:


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The purpose of performing antimicrobial susceptibility testing (AST) is to provide in vitro data to help ensure that appropriate and adequate antimicrobial therapy is used to optimize treatment outcomes. In addition, the AST data generated daily can be statistically analyzed on an annual basis to generate an antibiogram that reflects the antimicrobial susceptibility and resistance patterns of important pathogens that prevail in a particular hospital. These hospital-specific AST epidemiologic data provide valuable guidance to the clinicians for the appropriate selection of empiric therapy, prior to the availability of culture and susceptibility results that often takes 2–3 days. The purpose of the AST of the culture pathogen is to help clinicians correct and/or modify empiric therapy as soon as the results become available.

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