Vibrio cholerae

Authored by: Dongyou Liu

Manual of Security Sensitive Microbes and Toxins

Print publication date:  April  2014
Online publication date:  April  2014

Print ISBN: 9781466553965
eBook ISBN: 9781466553989
Adobe ISBN:


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Vibrio cholerae, the causal agent of cholera, was first isolated by Filippo Pacini in 1854. Transmitted via ingestion of contaminated seafood or water, the bacterium (called “vibrion” by its discoverer due to its motility) causes acute diarrheal infection with an incubation period of 2 h to 5 days. Spreading from its original reservoir in the Ganges delta in India during the nineteenth century, V. cholerae has killed millions of people across all continents in subsequent pandemics. In spite of continuous control efforts, cholera is still endemic in many countries in Africa, Asia, Middle East, and South and Central America, with an estimated 3–5 million cases annually, including >100,000 deaths.

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