PDT and the Immune System

Authored by: Fatma Vatansever , Michael R. Hamblin

Handbook Ofphotomedicine

Print publication date:  October  2013
Online publication date:  October  2013

Print ISBN: 9781439884690
eBook ISBN: 9781439884706
Adobe ISBN:

10.1201/b15582-40

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Abstract

Worldwide preclinical and clinical studies for more than two decades now have shown that photodynamic therapy (PDT) can be an integral part of a multimodal treatment approach to various cancer types and other malignancies. After the FDA’s approval of Photofrin, a commercially available hematoporphyrin derivative, in 1993 for patients with early and advanced stages of lung cancer, research utilizing PDT picked up speed globally. Today, PDT is a clinically approved therapeutic modality that is being successfully used for treatment of neoplastic and nonmalignant diseases.

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