Photodynamic Therapy for Increased Delivery of Anticancer Drugs

Authored by: Elodie Debefve , Yabo Wang , Thorsten Krueger , Hubert van den Bergh

Handbook Ofphotomedicine

Print publication date:  October  2013
Online publication date:  October  2013

Print ISBN: 9781439884690
eBook ISBN: 9781439884706
Adobe ISBN:


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The efficacy of any drug depends on its ability to reach its target. The drug delivery to a given tissue after systemic intravenous injection is influenced by the blood supply to the region of interest as well as transport through the vascular wall and the diffu-sion/convection through the interstitial space. To optimize the selective drug accumulation within the targeted area, one can play with three main parameters.

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