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13 Choline

Authored by: Janos Zempleni , John W. Suttie , Jesse F. Gregory III , Patrick J. Stover , Xinyin Jiang , Jian Yan , Marie A. Caudill

Handbook of Vitamins

Print publication date:  July  2013
Online publication date:  July  2013

Print ISBN: 9781466515567
eBook ISBN: 9781466515574
Adobe ISBN:


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Choline, a micronutrient commonly grouped with the B vitamins, is required for optimal nutrition. Choline-containing biomolecules, or derivatives, have a central role in many biological processes including neurotransmission, one-carbon metabolism, lipid metabolism, and signaling. The establishment of choline dietary recommendations, along with the availability of choline food composition tables, has led to a recent surge in the number of publications examining the role of choline in human health. This chapter provides a review of current knowledge related to food sources, metabolism, function, dietary requirements, and relationship to disease.

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