New Approaches for High-Speed, High-Resolution Imaging

Authored by: Gil Bub , Nathan Nebeker , Roger Light

Noval Advances in Microsystems Technologies and their Applications

Print publication date:  July  2013
Online publication date:  April  2016

Print ISBN: 9781466560666
eBook ISBN: 9781466560673
Adobe ISBN:

10.1201/b15283-10

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Abstract

Advances in image capture technologies have changed the way life science research is conducted. It is now relatively routine to capture image sequences from living cells and tissues at high rates, which allows scientists to directly visualize complex dynamic processes, such as embryo development, cell growth and division, and high-speed communication between excitable cells such as neurons and myocytes. However, image acquisition is still a bottleneck in many research projects. Living systems are inherently complex and operate over a wide range of space and timescales. Dynamics at subcellular space scales both influence and are influenced by tissue-level events. Fully capturing the dynamics of living systems is often beyond the capabilities of currently available imaging systems.

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