Methods of Stem Cell Lineage Analysis In Situ and in Cell Culture

Authored by: Andrei B. Borisov

Handbook of Molecular and Cellular Methods in Biology and Medicine

Print publication date:  December  2011
Online publication date:  April  2016

Print ISBN: 9781420069389
eBook ISBN: 9781439881958
Adobe ISBN:

10.1201/b11351-40

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Abstract

Successful translational and clinical applications of stem cell technology including regenerative medicine depend on clear understanding of the potential of engrafted precursors to proliferate and undergo terminal differentiation into normal, functionally active tissues. Methods of cell lineage analysis permit one to perform the identification of stem cell progeny and to trace its developmental fate in growing and regenerating organs and tissues.

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