Inhibition of Protein Synthesis

Authored by: Peter B. Kaufman , Ara Kirakosyan , Leland J. Cseke

Handbook of Molecular and Cellular Methods in Biology and Medicine

Print publication date:  December  2011
Online publication date:  April  2016

Print ISBN: 9781420069389
eBook ISBN: 9781439881958
Adobe ISBN:

10.1201/b11351-38

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Abstract

A protein synthesis inhibitor is a substance that stops or slows the growth or proliferation of plant, animal, or microbial cells by disrupting the processes that lead directly to the generation of new proteins (translation). Many antibiotics and toxins function as inhibitors of protein synthesis at different stages of translation: initiation, elongation, and termination. 1

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