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Challenges and Countermeasures in NIR Noninvasive Blood Glucose Monitoring

Authored by: Xu Kexin , Wang Ruikang K.

Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues

Print publication date:  December  2008
Online publication date:  December  2008

Print ISBN: 9781584889748
eBook ISBN: 9781584889755
Adobe ISBN:


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Over the past decades, noninvasive blood glucose monitoring has become an increasing important topic in the realm of biomedical engineering. Particularly, the introduction of optical approaches has brought exciting advances to this field. However, there is still no clinically feasible method for continuously monitoring of the in vivo human blood glucose concentration at the physiological level. This is probably because the instrumental response to the glucose specific signal is feeble compared to those of other compounds in the complex physiological system. An effective solution to this problem will represent a major advance in this field. This chapter analyzes the challenges faced by continuous in vivo blood glucose monitoring by use of near-infrared spectroscopy on both the aspects of methodological and instrumental implement. Some critical and imperative issues are identified and the promising and viable countermeasures are suggested at the end of this chapter.

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