Synthesis of l -Threonine and Branched-Chain Amino Acids

Authored by: L.B. Willis , P.A. Lessard , A.J. Sinskey

Handbook of Corynebacterium glutamicum

Print publication date:  March  2005
Online publication date:  March  2005

Print ISBN: 9780849318214
eBook ISBN: 9781420039696
Adobe ISBN:

10.1201/9781420039696.ch22

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Abstract

Threonine and the branched-chain amino acids, isoleucine, leucine, and valine, are synthesized by plants and many bacteria, but not by humans or other vertebrates. Since these compounds must be obtained in the diet, they are referred to as essential amino acids. The industrial production of amino acids has followed the rise in demand for these products as livestock feed supplements, pharmaceuticals, dietary supplements, and the source of new materials. Farmers routinely add amino acids, primarily lysine and threonine, to animal feeds in order to compensate for low levels of particular amino acids in the feedstuff, which is often derived from a single source, such as grain. Animal feed supplements account for a large segment of the global market for amino acids.

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