Dose Finding Clinical Trials Using R

Authored by: Naitee Ting , Ding-Geng (Din) Chen

Encyclopedia of Biopharmaceutical Statistics

Print publication date:  August  2018
Online publication date:  August  2018

Print ISBN: 9781498733953
eBook ISBN: 9781351110273
Adobe ISBN:

10.1201/9781351110273-140000080

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Abstract

In this entry, we illustrate the three approaches in analysis of dose-ranging trials which include the multiple comparison procedure (MCP), the modelling (MOD) approach, and the combined MCP-Mod approach. We illustrated these procedures with implementation in R with a real clinical trial data set.

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