Titration Design

Authored by: Marilyn A. Agin , Edward F. C. Pun

Encyclopedia of Biopharmaceutical Statistics

Print publication date:  August  2018
Online publication date:  August  2018

Print ISBN: 9781498733953
eBook ISBN: 9781351110273
Adobe ISBN:


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In the typical titration study, the response is defined according to some predetermined criterion, the dose is increased over time, and a subject may receive more than one dose level. This entry provides reasons and rationale for utilizing titration design in clinical trials as well as a sample data analysis.

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