Sample Size Calculation: Nonparametrics

Authored by: Hansheng Wang , Shein-Chung Chow

Encyclopedia of Biopharmaceutical Statistics

Print publication date:  August  2018
Online publication date:  August  2018

Print ISBN: 9781498733953
eBook ISBN: 9781351110273
Adobe ISBN:


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The objective of sample size calculation is to select an appropriate sample size so that not only the Type I error probability can be controlled under the specified level when the null hypothesis is true, but also to assure sufficient power for detection of a clinically meaningful difference when the alternative hypothesis is true. This entry reviews the sign test for comparing median and tests for independence and also provides simulation results and numerical examples.

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