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In This Chapter
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Factorial Designs
- Introduction
- History
- Orthogonal Designs for s m Factorial Experiments
- Orthogonal Designs for 2 n Factorial Experiments
- Case I: Interactions Within Subgroups
- Case II: Interactions Between Subgroups
- Case III: Interactions Between and Within Subgroups
- Orthogonal Designs for 3 m Factorial Experiments
- Orthogonal Designs for Mixed 2 n × 3 m Factorial Experiments
- Application of Mixed Factorial Design in Biomedical Research
- Example 1: Allele-Specific Polymerase Chain Reaction for Screening Point Mutation
- Example 2: Drug Interaction in a Clinical Study
- Conclusion
- References
Abstract
Factorial design theory is emerging as a fast, effective way of accumulating knowledge in most major sciences. This entry gives a brief review of the history of factorial design and some relevant theories developed recently and also touches on applications and clinical trials using the method.
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