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Clinical Research: Comparing Variabilities

Authored by: Yonghee Lee , Hansheng Wang , Shein-Chung Chow

Encyclopedia of Biopharmaceutical Statistics

Print publication date:  August  2018
Online publication date:  August  2018

Print ISBN: 9781498733953
eBook ISBN: 9781351110273
Adobe ISBN:


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In most clinical trials comparing a test drug and a control treatment effect is usually established by comparing mean response change from baseline of some primary study endpoints assuming that their corresponding variabilities are comparable. This entry gives several methods of comparing variablities and explores how to analyze the results.

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