Clinical Trials

Authored by: Kenneth B. Schechtman

Encyclopedia of Biopharmaceutical Statistics

Print publication date:  August  2018
Online publication date:  August  2018

Print ISBN: 9781498733953
eBook ISBN: 9781351110273
Adobe ISBN:

10.1201/9781351110273-130001048

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Abstract

This entry provides a broad overview of some general principles that govern the design and conduct of clinical trials. Specifically discussed are operational approaches to conducting a randomized and blinded trial and reasons why the absence of randomization, unblinded studies, and loss to follow-up can be major sources of bias in clinical trials.

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