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In This Chapter
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Bayesian Designs: Phase II Oncology Clinical Trials
- Introduction
- Phase II Clinical Trial Designs
- Single Threshold Design
- Dual Threshold Design
- Probabilities of Early Termination and Expected Sample Sizes
- Phase II Trial Using A Triplet Combination: Paclitaxel, Carboplatin, and Gemcitabine in Metastatic Nasopharyngeal Carcinoma
- Adaptations of The Designs
- Discussion
- References
Abstract
In this entry, we discuss two variants of a Bayesian two-stage design for clinical trials. Through a specific example, the entry also discusses how these designs can be used in practice.
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