Nanofiber Characterization by Raman Scanning Microscopy

Authored by: Alexander Khmaladze

21 Century Nanoscience – A Handbook

Print publication date:  April  2020
Online publication date:  April  2020

Print ISBN: 9780815384731
eBook ISBN: 9780429340420
Adobe ISBN:

10.1201/9780429340420-10

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Abstract

Electrospun nanofibers are becoming increasingly popular for applications in tissue engineering scaffolds, as they partially mimic the topography of the extracellular matrix. Nanofiber scaffolds promote in vivo-like salivary epithelial cell tissue organization and apicobasal polarization. Nanofibers alone provide surface topography and increased surface area that promote cellular attachment. Core/shell nanofibers, however, offer the versatility of incorporating two materials with different properties into one. Such synthetic materials can provide the mechanical and degradation properties required to make a construct that mimics in vivo tissue. Many variations of these fibers can be of interest. The challenge lies in the ability to characterize and quantify these nanofibers post fabrication.

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