Biosynthesis and Sequence Control of scl -PHA and mcl -PHA

Authored by: Camila Utsunomia , Nils Hanik , Manfred Zinn

The Handbook of Polyhydroxyalkanoates

Print publication date:  November  2020
Online publication date:  November  2020

Print ISBN: 9780367275594
eBook ISBN: 9780429296611
Adobe ISBN:


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This chapter gives an overview of the key elements that need to be considered for understanding and triggering the microstructure of polyhydroxyalkanoate (PHA) copolymers. This family of microbial biopolyesters offers a large potential considering its broad spectrum of possible material properties due to the diversity of comonomers. It is, therefore, of great interest to study and understand the influences on the molecular composition and composition distribution to valorize this potential. PHA biosynthesis is described considering substrates, microbial producers, the polymerizing enzyme class, and its spatial structure, as well as the kinetics of the PHA synthesis.

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