Testing Methodology of Preoperative Skin Preparation and Surgical Scrub as Over-the-Counter Drugs

Authored by: David K. Jeng

Handbook of Topical Antimicrobials

Print publication date:  September  2002
Online publication date:  September  2002

Print ISBN: 9780824707880
eBook ISBN: 9780203909256
Adobe ISBN:


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Almost a century has passed since Lister introduced the concept of asepsis with chemical antimicrobials. Today’s aseptic technique, however, is not much different from that of Lister’s era, namely, the application of preoperative skin preparation (POSP) on the body surface of the patients and the practice of surgical scrubbing (SS) and sterile gloving by surgeons and operating room (OR) nurses before surgery. However, evolution has taken place during recent decades in the synthesis of new antimicrobial chemicals and in the methods of application. The surgeons and OR nurses now have more antimicrobials of different chemical families to choose from than at any other time. The methods of qualification of POSP and SS are carefully governed by regulatory agencies, and the methods of application are described in detail by organizations such as the Association of Perioperative Registered Nurses (AORN).

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