Sporulation (Morphology) of Clostridia

Authored by: Ronald G. Labbé

Handbook on Clostridia

Print publication date:  March  2005
Online publication date:  March  2005

Print ISBN: 9780849316180
eBook ISBN: 9780203489819
Adobe ISBN:


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Bacterial spores are the most heat resistant of all living organisms, having been first described by Robert Koch and Ferdinand Cohn in 1876 [1]. In 1933, Bayne-Jones and Petrilli [2] first presented photographic evidence that bacterial sporulation involved a series of morphological changes in which one cell gives rise to one spore. In the 1960s and 1970s, the development of cultural methods resulting in the synchronous sporulation of a population of cells and refinement of electron microscope techniques resulted in detailed knowledge of the fine structure of bacterial spores and the sporulation process.

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