Carbohydrate Uptake by the Phosphotransferase System and Other Mechanisms

Authored by: Wilfrid J. Mitchell , Martin Tangney

Handbook on Clostridia

Print publication date:  March  2005
Online publication date:  March  2005

Print ISBN: 9780849316180
eBook ISBN: 9780203489819
Adobe ISBN:


 Download Chapter



With the exception of a few species that are capable of autotrophic growth, clostridia lead a heterotrophic existence relying on organic molecules as a source of carbon and energy [1]. The acquisition of these molecules from the surrounding environment is a prerequisite for growth and development, and it is therefore unsurprising that specific mechanisms exist to catalyze and control their uptake. The majority of uptake, or transport, processes in bacteria utilize metabolic energy to enable concentration of the substrate in the cytoplasm at a level that can support metabolism. These active transport processes are classified according to the form of energy involved; either high-energy phosphate bonds (ATP or PEP) or ion gradients (H+ or Na+). Examples of each of these categories have been found in clostridia, and while the transport systems have in many cases not been characterized in detail, it is clear that clostridia employ typical bacterial mechanisms to support nutrient uptake. This chapter will review the current understanding of uptake of carbohydrates by clostridial species; strains that have been reclassified as members of the genera Thermoanaerobacter and Thermoanaerobacterium [2] have not been included.

Search for more...
Back to top

Use of cookies on this website

We are using cookies to provide statistics that help us give you the best experience of our site. You can find out more in our Privacy Policy. By continuing to use the site you are agreeing to our use of cookies.