Quantitative Proteome Analysis of Clostridia

Authored by: Steffen Schaffer , Kai Thormann , Sandra Hujer , Peter Dürre

Handbook on Clostridia

Print publication date:  March  2005
Online publication date:  March  2005

Print ISBN: 9780849316180
eBook ISBN: 9780203489819
Adobe ISBN:

10.1201/9780203489819.ch2

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Abstract

Within the past decade molecular biology has gone through a transition from being an essentially reductionistic science focusing on one or few molecules at a time to a global science analyzing simultaneously whole classes of molecules, such as mRNA or protein pools. This paradigm shift has been initially triggered by the development of automated DNA sequencing methods, which allowed determination of the DNA sequence of entire bacterial genomes. Meanwhile, these techniques have been developed to a point, where deciphering eukaryal genomes is a feasible goal as has recently been demonstrated by sequencing the human genome.

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