Wet Granulation: End-Point Determination and Scale-Up

Authored by: Michael Levin

Encyclopedia of Pharmaceutical Science and Technology

Print publication date:  July  2013
Online publication date:  July  2013

Print ISBN: 9781841848198
eBook ISBN: 9781351124874
Adobe ISBN:

10.1081/E-EPT4-v5-48

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Abstract

Wet granulation is used mainly to improve flow and compressibility of powders, and to prevent segregation of the blend components. Particle size of the granulate is affected by the quantity and feeding rate of the granulating liquid.

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